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Education and Training

2015 Postdoctoral Scholar, Duke Molecular Physiology Institute

2015 Ph.D.  Zoology, North Carolina State University, Raleigh N.C.(Minors in Physiology & Molecular Biotechnology)

2010 B.S. Biology, Shaw University, Raleigh N.C. (Magna Cum Laude)

Publications

Douros, J.D., Lewis, A.G., Smith, E.P., Niu, J.J., Capozzi, M., Campbell, J., Tong, J., Wagner, C., Mahbod, P., Seeley, R., D’Alessio, D. Enhanced glucose control following vertical sleeve gastrectomy does not require a β-cell glucagon-like peptide 1 receptor.  Diabetes accepted manuscript DB180081.

Douros, J.D., Baltzegar, D.A., Reading, B.J., Borski, R.J. Novel role of leptin to stimulate glycolysis through STAT3 dependent mechanism in vertebrates. Frontiers in Endocrinology. In Revision. 

Anderson, K.A., Huynh, F.K., Fisher-Wellman, K., Stuart, J.D., Peterson, B.S.,Douros, J.D., Wagner, G.R., Thompson, J.W., Madsen, A.S., Green, M.F., Sivley, R.M., Ilkayeva, O.R., Stevens, R.D., Backos, D.S., Capra, J.A., Olsen, C.A., Campbell, J.E., Muoio, D.M., Grimsrud, P.A., Hirschey, M.D.SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion. Cell Metabolism 25(4), 838-855.e15 (2017) PMID 28380376.

Douros J.D.,Baltzegar DA, Reading BJ, et al., Metabolic stress stimulates leptin A (LepA) in the tilapia (Oreochromis mossambicus): Implications for the regulatory interaction between LepA and the hepatosomatic growth axis. Gen Comp Endocrinology 240, 227-237 (2017). PMID 27449341.

Won, E.T., Douros, J.D., Hurt, D.A., Borski, R.J. Leptin stimulates hepatic growth hormone receptor and insulin-like growth factor gene expression in a teleost fish. Gen Comp Endocrinology 229, 84-91 (2016). PMID 26853487.

Douros, J.D., Baltzegar, D.A., Breves, J.P., Lerner, D.T., Seale, A.P., Gordon Grau, E. & Borski, R.J. Prolactin is a major inhibitor of hepatic Leptin A synthesis and secretion: Studies utilizing a homologous Leptin A ELISA in the tilapia. Gen Comp Endocrinol(2014). PMID 24662392.

Baltzegar, D.A., Reading, B.J., Douros, J.D.& Borski, R.J. Role for leptin in promoting glucose mobilization during acute hyperosmotic stress in teleost fishes. Journal of Endocrinology220, 61-72 (2014). PMID 24194509

Fellowships

2017: Ruth L. Kirschstein NRSA Individual Postdoctoral Fellowship (1F32DK115031-01)National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

2016: Ruth L. Kirschstein NRSA Institutional Research Training Grant (T32DK007012) National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

2011: Graduate Research Fellowship, U.S. Department of Education Graduate Assistance in Areas of National Need (GAANN) Fellowship

Scholarships  and Awards

2017: Keystone Symposia Future of Science Fund Scholarship, Gastrointestinal Control of Metabolism Symposia(Z6)

2016: Duke Scholars in Molecular Metabolism

2016: Duke-National University of Singapore Postdoctoral Research Exchange Program Fellowship

2015: Best Presentation Runner-up: North American Society of Comparative Endocrinologists Biennial Meeting 

2015: Travel Award: North American Society of Comparative Endocrinologists Biennial Meeting 

2015 Certificate of Accomplishment in Teaching Program (N.C. State University)

2013: Graduate Teaching Assistantship (N.C. State University)

2009: Medical Education Development Program Scholar (UNC-CH School of Medicine)

2007: Athletic Scholarship, Basketball (Shaw University)

Presentations

2018: Vertical sleeve gastrectomy (VSG) rapidly and weight-independently enhances intrinsic β celltriggering and amplifying pathways for insulin secretion.Douros, J.D., Niu, J., Fisher-Wellman, K., Gregg, T., Sdao, S.,Bharadwaj, M., Molina, A., Merrins, M., Petretto, E., Tong, J., Campbell, J., D’Alessio, D. Keystone Symposia, Frontiers in Islet Biology and Diabetes (B3).

2017: Does Bariatric Surgery Build Better Beta-cells? Douros, J.D., Niu, J., Tong, J., Sdao, S. Merrins, M., Petretto, E., Campbell, J., D’Alessio, D. American Diabetes Association 77thScientific Sessions. 

2017:  Increased Glucose-Dependent Insulinotropic Polypeptide (GIP) Secretion and Signaling Improves Beta-Cell Function following Vertical Sleeve Gastrectomy (VSG). Douros, J.D., Niu, J., Tong, J., Campbell, J., D’Alessio, D. Keystone Symposia, Gastrointestinal Control of Metabolism (Z6).

2015:Novel role of leptin to stimulate glycolysis through STAT3 dependent mechanism in vertebratesDouros, J.D.,Baltzegar, D.A., Reading, B.J., Borski, R.J. 3rd Biennial Conference of the North American Society for Comparative Endocrinology

2015:Who’s in charge here? How gut hormones drive the brain and behaviorDouros, J.D. North Carolina Museum of Sciences Brain Awareness Week Symposium

2015:Novel role of leptin to stimulate glycolysis through STAT3 dependent mechanism in vertebratesDouros, J.D.,Baltzegar, D.A., Reading, B.J., Borski, R.J. W.M Keck Center for Behavioral Biology Student/Postdoctoral Fellow Symposium.

2013:Leptin Stimulates Hepatic Growth Hormone Receptors and Insulin-like Growth Factor Expression: Possible Function in Enhancing GH-Mediated Anabolic Processes in Fish. Douros, Jonathan, Won, Eugene, Baltzegar, David, Borski, Russell. The Statistics and Zoology Graduate Student Symposium

2013:Leptin Stimulates Hepatic Growth Hormone Receptors and Insulin-like Growth Factor Expression: Possible Function in Enhancing GH-Mediated Anabolic Processes in Fish.Douros, Jonathan, Won, Eugene, Baltzegar, David, Borski, Russell. World Aquaculture Society International Symposium 

2012:Development and Validation of a Homologous ELISA to Tilapia Leptin. NCSU Molecular Biotechnology Symposium

2011:Production and Purification of Recombinant Tilapia (Oreochromis mossambicus) Leptin. NCSU Molecular Biotechnology Symposium

Research Experience

2015-present: Postdoctoral Scholar, Duke University 

2010-2015: Doctoral Research, North Carolina State University

2010: Undergraduate Research, North Carolina State University

2010: Undergraduate Research, North Carolina State University

Teaching Experience

2011-2014:Cellular and Molecular Biology Laboratory: Bio 183

2012: Endocrinology (Bio 492/594)

2010:  Ecology, Evolution, and Biodiversity LaboratoryBio 181

Undergraduate Mentorship

2015: Meredith Meyer, currently completing B.S. Biology at NCSU

2014-2015: Jordan Taylor, currently pursuing M.D. at V.A. Tech Corilian School of Medicine

2015: Alex Yllanes, currently pursuing Ph.D. Neurophysiology at East Carolina University

2012-2013 Everett Wilson, currently pursuing M.A. Physiology at NCSU

Professional/Educational Societies

2017: Endocrine Society

2016: American Diabetes Association

2015: North American Society for Comparative Endocrinology

2014-2015: The W.M. Keck Center for Behavioral Biology

2010-2015: American Association for the Advancement of Sciences

2013: World Aquaculture Society

2010-2015: N.C. State Graduate Student Association

2009: Alpha Chi National Honors Society